BeLoged

Orhan Karsligil's Ideas, Thoughts and Collection of Resources

Rational Design of Antimicrobial Peptides

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Start Date: 2005
Last Update: 09/29/2009

Members: Orhan Karsligil
               Tanguy Chau
Others:    Prof. Greg Stephanopoulos
               Chris Loose
               Kyle Jensen

Objective:
Using known antimicrobial peptides from Nebraska Database extract motifs that can be used to create new active peptides with desired properties.

Technologies and Methodologies Used:
Motif Discovery
Scoring Algorithms
Clustering Algorithms
Cleanup Algorithms
Tiling Algorithms
Design Algorithms

Status Update:
After the 4th phase of design we managed to create a robust and rigorous enough algorithm that can generate consistently active peptides.

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